| Objective To explore the risk factors, clinical characteristics, treatment strategies and prognosis of vasa previa. Methods The clinical data of 14 cases of vasa previa in pregnant women from January 2014 to September 2017 admitted to the Shenyang women’s and Children’s Hospital were retrospectively analyzed. The risk factors, clinical features and prognosis were summarized and analyzed. Results Among the 14 cases with vasa previa, 9 cases (64.3％) were diagnosed by prenatal abdominal ultrasound, the average gestational age of prenatal diagnosis was 29+5 weeks, and 5 cases were diagnosed after delivery. All 14 cases had high risk factors, including 2 cases of complete placenta previa, 2 cases of low-lying placenta, 2 cases of spontaneous twins, 3 cases of cord velamentous insertion, 3 cases of low-lying placenta with cord velamentous insertion, and 3 cases of low-lying placenta with battledore placenta. The 9 cases with prenatal diagnosis of vasa previa had cesarean termination of pregnancy, and the perinatal outcomes were all good. As for the 5 cases that were diagnosed after delivery, 1 case of emergent cesarean delivery because of refusing vaginal delivery, 1 case of premature normal delivery of twins with one of the newborns with hypospadias, 1 case of emergent cesarean delivery because of relatively large fetus, 1 case with rupture of membrane had emergent cesarean delivery because of the fetal distress, all the above cases had good perinatal outcomes. The other one case with premature rupture of membrane resulted in a ruptured fetal vessel and fetal death. Conclusion Ultrasound is the most commonly used and reliable method for prenatal diagnosis of vasa previa. In order to improve the detection rate, we should pay attention to the vasa previa in women with high risk factors such as placental previa or low-lying placenta, multiple pregnancy, and the cord velamentous insertion at the ultrasound examination. In addition, vasa previa should be suspected when there is vaginal bleeding combined with fetal distress so emergency cesarean section can be implemented as soon as possible to improve perinatal outcome.