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冠状动脉慢性完全闭塞治疗策略
黄榕翀1, 郭 雷2
1.首都医科大学附属北京友谊医院 心血管中心,北京 100050;2.大连医科大学附属第一医院 心内科, 辽宁 大连 116011
摘要:
冠状动脉慢性完全闭塞性病变(chronic total occlusion,CTO)约占所有冠心病患者的15%~25%,是冠心病介入治疗领域最后的“壁垒”,而且对患者的生活质量和长期预后有不利影响。随着新型介入治疗器械、CTO介入治疗新技术和术者操作水平不断进步,接受经皮冠状动脉介入治疗(percutaneous coronary intervention, PCI)手术的成功率甚至可达90%。但目前对于CTO是否需要开通存在较大争议,以及临床获益尚不明确。本文就最新的研究对CTO的治疗策略作一介绍。
关键词:  冠状动脉慢性完全闭塞性病变  经皮冠状动脉介入治疗  治疗策略
DOI:10.11724/jdmu.2019.04.01
分类号:R543.3+1
基金项目:基金项目:中国心血管联盟V.G中青年研究基金项目(2017-CCA-VG-046);北京合众关爱心脏健康基金会“立信扬帆”优化抗栓科研基金项目(BJUHFCSOARF201801-02);大连医科大学转化医学专项基金项目(2015003)
Progress in treatment strategies for chronic total coronary occlusion
HUANG Rongcong1, GUO Lei2
1.Cardiovascular Center,Beijing Friendship Hospital,Capital Medical University,Beijing 100050, China;2.Department of Cardiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011, China
Abstract:
Coronary chronic total occlusion (CTO) lesions account for approximately 15%-25% of patients with coronary heart disease, are the last "barrier" in the field of coronary intervention, and have adverse effects on patients' quality of life and long-term prognosis. With the new interventional therapy devices, new CTO interventional techniques, and advanced operational skills of operators, the success rate of CTO percutaneous coronary intervention (PCI) reaches 90% at experienced centers. However, there are controversies about whether CTO lesions need to be opened and the clinical benefits are unclear. This review gives a brief introduction to the progress of CTO treatment strategies according to the latest research.
Key words:  CTO  PCI  therapeutic strategies